Explore Real Clinical Cases

Explore real cases with stories and pictures

Explore Our On-Line Learning Content

Enhance your knowledge of tumors and their management

High-Grade surface osteosarcoma

Summary

High grade periosteal osteosarcoma (also known as high grade surface osteosarcoma) accounts for less than 1% of all osteosarcoma. The only difference between conventional osteosarcoma and high-grade per osteal osteosarcoma is the location of the latter on the surface of the bone.

High grade periosteal osteosarcoma appears malignant on plain x-ray. There is irregular cortical destruction as well as irregular periosteal reaction.
Complete Information on this Tumor
Introduction and Definition: 

High grade periosteal osteosarcoma (also known as high grade surface osteosarcoma) accounts for less than 1% of all osteosarcoma. The only difference between conventional osteosarcoma and high-grade per osteal osteosarcoma is the location of the latter on the surface of the bone.

X-Ray Appearance and Advanced Imaging Findings: 
High grade periosteal osteosarcoma appears malignant on plain x-ray. There is irregular cortical destruction as well as irregular periosteal reaction. Bone marrow infiltration is visible on MRI.
Histopathology findings: 
High grade periosteal osteosarcoma appears identical to conventional osteosarcoma microscopically.
Treatment Options for this Tumor: 
The tumors are treated similarly to conventional osteosarcoma and have the same prognosis.
Suggested Reading and Reference: 
References Bloem, JL and HM Kroon, Osseous Lesions, Radiologic Clinics of North America, 31(2):261-277, March 1993. Bullough, Peter, Orthopaedic Pathology (third edition), Times Mirror International Publishers Limited, London, 1997. Huvos, Andrew, Bone Tumors: Diagnosis. Treatment and Prognosis, W.B. Saunders, Co., 1991.
»